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The Brightening Solution

Maximum-strength treatment for stubborn melasma.

Best for: Stubborn or resistant melasma. Choose this if your pigmentation has not improved with other treatments or runs deep.

Made to treat:

Stubborn Melasma Deep Pigmentation Resistant Dark Spots Uneven Tone Photoaging

43+ Reviews

$69/month

No Hidden Fees

Cancel Anytime

24/7 Support

Free Delivery

Skip or Delay Refills

Breadcrumb Nav
Breadcrumb Nav

The Brightening Solution

Maximum-strength treatment for stubborn melasma.

$69/month

Best for: Stubborn or resistant melasma. Choose this if your pigmentation has not improved with other treatments or runs deep.

Made to treat:

Stubborn Melasma Deep Pigmentation Resistant Dark Spots Uneven Tone

00+ Reviews

No Hidden Fees

Cancel Anytime

24/7 Support

Free Delivery

Skip or Delay Refills

Multi-mechanism prescription correction

Includes hydroquinone for stronger pigment control

Designed for deeper discoloration

Accelerates visible tone improvement

This solution may be ideal for people whose skin is

  • Dealing with deep or persistent melasma that has not responded to other treatments

  • Looking for a stronger prescription with hydroquinone for faster pigment correction

  • Experiencing discoloration that covers larger areas of the face

  • Prepared for a maximum-strength brightening formula, as assessed by a prescriber

A licensed prescriber will determine whether it is appropriate for you. Compounded medications are not FDA approved.

Who it’s For

Refine may be ideal for people whose skin is

  • Breakout prone or prone to glogged looking pores

  • Looking a little dull or uneven in tone

  • Showing early signs of sun related aging

  • Able to comfortably tolerate a prescription retinoid, as assessed by a prescriber

A licensed prescriber will determine whether it is appropriate for you. Compounded medications are not FDA approved.

Proven ingredients, personalized prescriptions

Hydroquinone

The gold standard prescription brightening agent that directly inhibits melanin production to correct deep, stubborn pigmentation.

Kojic Acid

Works alongside hydroquinone to slow melanin formation and support an even, brighter skin tone.

Tretinoin

Drives cell turnover to lift deeper pigmentation and accelerate the visible fading of dark spots.

Niacinamide

Helps even out tone, reduce irritation, and support the skin barrier throughout maximum-strength brightening treatment.

Results you can see. Confidence you can feel!

My melasma had been resistant to everything I tried. The advanced formula was the first treatment that made a visible difference. My skin tone is the most even it has been in over a decade.

Rosa M.

I had been dealing with deep pigmentation from pregnancy for years. DermClick prescribed the advanced formula and within two months the change was undeniable.

Angela F.

I tried the gentler option first but my melasma needed something stronger. The advanced formula through DermClick finally gave me the correction I needed."

Claudia V.

Not sure which

solution is right for you?

Take our 2-minute skin quiz and

we’ll match you to the right formula.

Not sure which solution is right for you?

Take our 2-minute skin quiz and we’ll match you to the right formula.

© Copyright 2025 DermClick. All Rights Reserved.

© Copyright 2025 DermClick.

All Rights Reserved.